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What is Methyl Folate (L-5-MTHF) by Douglas Laboratories?
Methyl Folate by Douglas Laboratories supplies 1,000 mcg of biologically active folate called (6S) 5- methyltetrahydrofolate (5-MTHF).
What does Methyl Folate (L-5-MTHF) do?
Folate is a water-soluble essential B vitamin found in many foods, including leafy green vegetables, citrus fruits and beans.
Research has established that supplementation with folate before and during the first two months of pregnancy can support proper neurological development in the fetus.
Additionally, folate plays a key role in the metabolism of homocysteine.
Homocysteine is a sulfur containing amino acid that is created in the body from methionine, an essential amino acid derived solely from dietary intake.
High plasma levels of homocysteine appear to injure the vasculature, impairing the functional abilities of endothelial and smooth muscle cells.
Metafolin folate is a patented, natural form of (6S) 5-methyltetrahydrofolate (5-MTHF). 5-MTHF is the naturally occurring, predominant form of folate commonly found in cells and is essential for overall health, as it participates as a cofactor in a reaction that involves the remethylation of homocysteine to methionine. Unlike synthetic folic acid, 5-MTHF can be used directly by the body, without the need for an additional conversion via the enzyme 5,10-methylenetetrahydrofolate reductase (MTHFR).
In certain populations, the body’s ability to convert folic acid to 5-MTHF by use of this enzyme may be compromised due to genetic differences.
Metafolin contains only the S isomer of 5-MTHF and has been shown to be the only form of folate to be able to cross the blood-brain barrier.
Metafolin does not appear to mask the anemia associated with a vitamin B12 deficiency and presents no risk of an accumulation of unmetabolized folic acid in the body.
Who should use Methyl Folate (L-5-MTHF)?
Methyl Folate is a useful dietary supplement for those individuals that prefer a high dose active form of folic acid called (6S) 5-MTHF.
Ingredients
1000mcg Folate (calcium L-5 methyltetrahydrofolate Metafolin)
Non-Medicinal Ingredients: Cellulose, dicalcium phosphate dihydrate, croscarmellose sodium, magnesium stearate, silica, stearic acid.
Dosage
Take 1 tablet daily or as directed by your healthcare practitioner.
Important Information
Folate supplementation can mask Vitamin B12 deficiency; consult your healthcare practitioner if you are uncertain whether or not you are taking adequate Vitamin B12.
Do not use if cap seal is broken.
For optimal storage conditions, store in a cool, dry place.
Keep out of reach of children.
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We strive to provide accurate product information, but manufacturers may sometimes change their ingredient lists, which may result in differences between the information displayed on our website and the information on the product packaging. We recommend that you do not rely solely on the information presented on the site and always read labels, warnings, and directions before using or consuming a product. For additional information about a product, please contact the manufacturer. The information provided on this site is for reference purposes only and does not replace the advice of a licensed healthcare professional. You should not use this information to diagnose or treat a health problem or disease. Contact a healthcare professional immediately if you suspect you have a health problem.